serum copper article

serum copper article

Serum copper levels are associated with bone mineral ...

May 31, 2018 · Moderate serum copper levels are critically important for bone health. Lower serum copper levels are significantly associated with decreased BMD in the total femur and femoral neck. Higher serum copper levels are significantly associated with increased total fracture, especially in men.

Serum zinc and copper in patients with COVID-19 and

Accordingly, low serum levels of zinc and copper were observed at ICU admission and those with the higher serum concentrations had significantly lower mortality [10, 11]. Recently, an association between low zinc levels and the severity of acute respiratory distress syndrome has been shown for patients with severe COVID-19 [12].

Associations of Dietary and Serum Copper with

Feb 01, 2008 · Serum copper concentration was determined by flame atomic absorption spectrometry (5110 PC spectrometer Perkin-Elmer), which measured both bound and unbound serum copper with a CV of 3.6–4.9%. The evaluation of TAS levels in samples was based on the reduction of Cu ++ into Cu + by the action of all present antioxidants.

Copper Blood Level - an overview | ScienceDirect Topics

Copper. Serum copper is the most useful marker of copper status, effective in both replete and depleted persons. The tight homeostatic regulation of copper levels in circulation generally restricts major perturbations in levels to the extremes of dietary intake. Serum copper is frequently measured by ICP-MS, although AAS is a common alternative.

Increased serum copper and decreased serum zinc levels

高达12%返现 · Original Articles; Published: December 1997; Increased serum copper and decreased serum zinc levels in children with iron deficiency anemia. Aydin Ece 1, Bekir Sami Uyamik 2, Akin IŞcan 1, Pelin Ertan 1 & M. Ramazan Yiğitolu 2 Biological Trace Element Research volume 59, pages 31–39 (1997)Cite this article

Relationship between Serum Copper, Ceruloplasmin, and

Aug 01, 2005 · Serum copper is influenced by age, acute-phase reactions, pregnancy, many anemias, and medication (oral contraceptives and antiepileptics) . Furthermore, ∼2% of the population who are heterozygous for P-type ATPase mutations have low copper and ceruloplasmin concentrations . Many tests can be used to investigate patients who may have Wilson ...

Copper: Reference Range, Interpretation, Collection and

Feb 16, 2017 · Serum ceruloplasmin is also a valuable test and can be used to determine the free serum copper. Copper reference ranges are as follows: Free serum copper: 1.6-2.4 μmol/L or 10-15μg/dL [ 1] Total copper: 10-22 μmol/L or 63.7-140.12 μg/dL [ 2] Serum

Role of copper in human neurological disorders | The ...

Sep 01, 2008 · Binding of copper ions destabilizes native β2-microglobulin , and changes in renal tubular dysfunction may parallel the serum concentrations of copper . CONCLUSIONS. Recent evidence highlights the important role of copper in the development

Serum Zinc, Copper, and Other Biometals Are Associated ...

Apr 15, 2021 · In view of significant bidirectional changes of serum Cu and Zn levels, serum copper-to-zinc (Cu/Zn) ratio was also evaluated in the studied cohort. Cu/Zn values were found to increase gradually in association with COVID-19 severity. Specifically, patients with mild, moderate, and severe COVID-19 were characterized by 18%, 39%, and 39% higher ...

Serum Ultrafiltrable Copper, Total Copper and ...

Nov 01, 1993 · Serum copper and caeruloplasmin concentrations are elevated in various carcinomas, but it is not known whether the rise in serum copper is due to elevation of caeruloplasmin alone or whether it is also due to the elevation of ‘free’ copper. We therefore determined ultrafiltrable copper to answer this question.

Serum Copper Level Significantly Influences Platelet Count ...

Dec 12, 2015 · Changes in serum micro nutrients levels affect a number of critically important metabolic processes; these could potentially influence blood counts and ultimately disease presentation in patients with sickle cell anemia (SCA).To evaluate the influence of serum micro-nutrients levels; zinc, copper, selenium and magnesium on blood counts in steady state SCA patients.A cross sectional study that ...

Copper deficiency, a new triad: anemia, leucopenia, and ...

Sep 19, 2017 · Estimated copper requirement in patients receiving total parenteral nutrition is approximately 0.3 mg/day in the adult . Dietary deficiency is rare but it is possible. In our patient, rapid increase in serum copper level after oral supplementation suggest dietary deficiency the most likely cause. Weight loss over several months also points ...

Serum copper, zinc, and iron levels, and markers of ...

Sep 01, 2017 · Elevation of serum Cu levels without a simultaneous change in circulating Cp concentrations may be indicative of increased “free copper” levels. Moreover, taking into account the role of Cp in iron transport, diabetes-related perturbations in Cp levels may at least partially contribute to alteration in iron metabolism.

Serum Zinc, Copper, and Zinc/Copper in Healthy Residents ...

Apr 02, 2009 · Copper deficiency is unusual in people with an adequate diet, but copper deficiency in serum is usually associated with Menke’s syndrome [1–3], iron deficiency anemia, leucocytopenia, reduction of ceruloplasmin and erythrocyte copper superoxide dismutase (SOD), irregularity of heart rate, neural degeneration, and osteoporosis, whereas ...

Serum zinc and copper in people with COVID-19 and zinc ...

Accordingly, low serum levels of zinc and copper have been observed at ICU admission, and those with higher serum concentrations have shown significantly lower mortality [10,11]. Recently, an association between low zinc levels and the severity of acute respiratory distress syndrome has been shown for people with severe COVID-19 [12] .

Relationship between Serum Copper, Ceruloplasmin, and Non ...

Aug 01, 2005 · Serum copper is influenced by age, acute-phase reactions, pregnancy, many anemias, and medication (oral contraceptives and antiepileptics) . Furthermore, ∼2% of the population who are heterozygous for P-type ATPase mutations have low copper and ceruloplasmin concentrations . Many tests can be used to investigate patients who may have Wilson ...

Increased serum copper and decreased serum zinc levels in ...

Original Articles; Published: December 1997; Increased serum copper and decreased serum zinc levels in children with iron deficiency anemia. Aydin Ece 1, Bekir Sami Uyamik 2, Akin IŞcan 1, Pelin Ertan 1 & M. Ramazan Yiğitolu 2 Biological Trace Element Research volume 59, pages 31–39 (1997)Cite this article

Copper: Reference Range, Interpretation, Collection and Panels

Feb 16, 2017 · Serum ceruloplasmin is also a valuable test and can be used to determine the free serum copper. Copper reference ranges are as follows: Free serum copper: 1.6-2.4 μmol/L or 10-15μg/dL [ 1] Total copper: 10-22 μmol/L or 63.7-140.12 μg/dL [ 2] Serum

Serum copper to zinc ratio: Relationship with aging and ...

Nov 01, 2015 · The serum concentrations of copper (Cu) and zinc (Zn) are strictly regulated by compensatory mechanisms that act to stabilize them within certain ranges of nutritional intake. However, there are mechanisms that are built to decrease serum concentration of Zn and to increase serum concentration of Cu in the presence of inflammatory conditions ...

Non-ceruloplasmin bound copper and ATP7B gene variants in ...

ATP7B, a protein mainly expressed in the hepatocytes, is a copper chaperone that loads the metal into the serum copper–protein ceruloplasmin during its synthesis and also escorts superfluous copper into the bile, by a sophisticated trafficking mechanism. Impaired function of this ATPase is associated with a Mammalian Copper Transport and Related Disorders

[Effect of anesthesia with halothane on serum ...

[Effect of anesthesia with halothane on serum concentrations of iron, copper, manganese, zinc and cobalt in humans, determined by continuous flow injection and atomic absorption spectrophotometry] Acta Cient Venez. 1988;39(2):130-4. [Article in Spanish] Authors O ...

Free copper in serum: An analytical challenge and its ...

Jan 01, 2018 · Compparison of ultrafiltration and solid phase extraction for the separation of free and protein-bound serum copper for the Wilson’s disease diagnosis. Clin. Chim. Acta, 345 (2004), pp. 113-121. Article Download PDF View Record in Scopus Google Scholar.

Serum copper: a marker of disease activity in rheumatoid ...

Serum copper concentrations were measured in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), osteoarthritis (OA), and in healthy controls. Median serum copper concentrations were raised significantly in RA and AS, but not in OA. Serum copper in RA correlated significantly with a number of disease activity markers--for example erythrocyte sedimentation rate (ESR), C ...

The Association between Serum Copper and Anemia in the ...

Nov 16, 2005 · Furthermore, copper levels are known to be elevated in inflammation. Thus, unrecognized cases of anemia of chronic illness might explain the observed association between high serum copper levels and unexplained anemia. On the other hand, subjects with low serum copper levels and unexplained anemia might have nutritional deficiency.

Research Article Serum Copper and Haematological Values

Research Article Serum Copper and Haematological Values of Sheep of Different Physiological Stages in the Dry and Wet Seasons of Central Trinidad A.Mohammed, 1 M.Campbell, 2 andF.G.Youssef 3 Eastern Caribbean Institute of Agriculture and Forestry, Faculty of

Altered serum copper homeostasis suggests higher oxidative ...

uited. Analyses included serum levels of total copper (TCu), copper ions (Cu+), small molecule copper (SMC), ceruloplasmin (CP), Cu/Zn superoxide dismutase 1 (SOD1), urinary copper, and the activities of serum CP and SOD1. The serum TCu and urinary copper levels in patients with CHB were significantly higher than the controls (P = .04 and .003), while the serum Cu+ was lower than the controls ...

ORIGINAL ARTICLE Significance of serum levels of copper ...

ORIGINAL ARTICLE ABSTRACT BACKGROUND: To measure the levels of trace elements (Serum Copper, Zinc) in patients of Hypertension. Serum copper and serum zinc were estimated in fifty (50) hypertensive patients and fifty (50) age-and sex-matched apparently healthy well nourished controls by colorimetric method using Erba XL 640 fully auto analyzer.

Copper Supplementation, A Challenge in Cattle

Oct 15, 2020 · Serum/plasma copper concentration is a poor indicator of copper loading of the liver [79,80,81,82]; in fact, cows considered to be deficient or in the low-normal part of the reference range on the basis of evaluation of serum copper concentrations have been found to be at or near a toxic state on the basis of necropsy results or examination of ...

Serum levels of copper, iron, and manganese in women with ...

Dec 01, 2019 · The obtained data demonstrate increased serum copper and manganese levels in pregnancy, whereas women with reproductive health problems did not differ significantly from the controls. The lack of such increase in miscarriage and infertility without significant group difference with healthy controls may be indicative of impaired metal handling ...

Copper: Reference Range, Interpretation, Collection and Panels

Feb 16, 2017 · Serum ceruloplasmin is also a valuable test and can be used to determine the free serum copper. Copper reference ranges are as follows: Free serum copper: 1.6-2.4 μmol/L or 10-15μg/dL [ 1] Total copper: 10-22 μmol/L or 63.7-140.12 μg/dL [ 2] Serum

Postpartum Depression and Role of Serum Trace Elements

In pregnancy estrogens, by increasing hepatic ceruloplasmin synthesis, and by increasing serum copper concentrations, the noticeable elevation in maternal serum copper during the course of pregnancy is well established (43, 68). Based on these considerations, studies have been done on the relationship of Cu levels to mental depression, but ...

Serum Copper Level in Patients with Heart Failure and its ...

Dec 12, 2020 · Heart Failure Etiology Serum Copper Level 1. Background Congestive heart failure (CHF) is a debilitating disorder that affects 1-2% of the general population and occurs due to the inability of the heart to pump blood to the bloodstream.

The association of serum copper with ceruloplasmin and ...

The association of serum copper with ceruloplasmin and zinc with folic acid levels in recurrent pregnancy loss in Iraqi Women Olaa Riad Kadim 1, Shatha M. J. Al-Khateeb 1, Esraa H Humadi 2 1 Department of Chemistry and Biochemistry, College of Medicine, Al-Mustansiryia University, Baghdad, Iraq 2 Department of Obstetrics and Gynaecology, College of Medicine, Al-Mustansiryia University,

Effect of oral contraceptive progestins on serum copper ...

Sep 30, 1998 · Objectives: Recent epidemiologic studies have shown an increased mortality from cardiovascular diseases in people with higher serum copper levels. Even though higher serum copper concentration in ...

Association between serum copper levels and prevalence of ...

May 26, 2020 · Hyperuricemia is a condition characterized by abnormally elevated levels of serum uric acid (UA). The reported prevalence of hyperuricemia has